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Another AD study, focused on targeting CD38, showed that CD38 knockdown in APP Swe mutation-expressing transgenic mice enhanced NAD + levels and reduced A plaques in brain extracts, mirrored by some improvement of cognitive performance 270,274
Radioactivity was measured with the TopCount scintillation counter (Perkin Elmer)
Risstalpers C, Verleunmooijman MCT, Trapman J, Brinkmann AO
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