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Iron must be maintained at balanced levels within the body too much can cause toxicity and too little may lead to impairment of optimal health outcomes

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Specifically, MLL1 interacts directly with WD repeat domain 5(WDR5) to initiate DDR, involving phosphorylated ataxia telangiectasia mutated (ATM) kinases/ATM and Rad-3-related (ATR) kinases/and checkpoint kinase(Chk), and the expression of -H2AX

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Wu G, Fang YZ, Yang S, Lupton JR, Turner ND

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