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In vivo, intrastriatal 3-HK alone produces limited neuronal loss, but co-administration with QA results in synergistic excitotoxic and oxidative injury that is attenuated by NMDAR antagonists and free radical scavengers [156]
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Presented for research literature review only Moutiez M et al
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This makes telomere length the limiting factor for cellular division: when they become too short, the cell they're attached to ceases to divide and enters senescence
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