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Understanding these potential reactions can help patients and healthcare professionals identify and manage them appropriately

While Tirzepatide has not run a dedicated osteoarthritis trial, weight loss of any significant magnitude reliably reduces mechanical load on weight-bearing joints

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However, since Mounjaro dosage is increased every four weeks (up to a maximum of 15 mg weekly) until the best dose is found for each patient, the body may need to readjust every time the dose is changed