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Mechanistically, inhibition of complex I is expected to reduce mitochondrial ubiquinol (CoQ 10 H 2 ) levels, promoting lipid peroxidation and sensitizing cells to ferroptosis 107

Starting lower allows your body to acclimate and significantly reduces the risk of severe gastrointestinal distress during the transition

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Dietary approaches should focus on nutrient-dense, whole foods with adequate protein intake to help preserve lean muscle mass during weight loss

these events were primarily of mild severity and most patients recovered while on treatment