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Further, deleting GLP-1Rs in ME tanycytes has similar effects [125], suggesting that liraglutide first activates GLP-1Rs in ME tanycytes to then gain access to and activate GLP-1R-expressing hypothalamic neurons and exert its effects on energy balance
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Cadaverine has also been implicated in transient receptor potential cation channel subfamily V member 1 (TRPV1) receptor activation in neurons, leading to itch [242]
doi: 10.1111/jcmm.14520 129 BaiYCuiWXinYMiaoXBaratiMTZhangCet al
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