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3ad), indicating that GSH prevented LOsG-induced ROS production in pancreatic cells

pylori colonization also negatively affects the expression of antioxidant proteins, along with epigenetic modifications and DNA methylation, such as GATA-4, GATA-5 and TWIST-1 (88), as well as miRNAs dysregulation, such as mir-21, mir-92a, mir-27a, mir-146a, mir-326, mir-155 and mir-663 (73, 89)

The redox cycling enzymes thioredoxin, thioredoxin reductase, sulfiredoxin, peroxiredoxin, GSH peroxidase, superoxide dismutase 1, and catalase, and several GSH S-transferases, which are the enzymes mediating the elimination of ROS, are all Nrf2 targets (242)

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