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Human data is still limited, so results vary and it's used under supervision
That does not automatically make it worse, but it does mean the research question is different
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The trial reported a hazard ratio of 1.76 for retinal complications within the first 1 to 2 years of treatment
Possible Side Effects Observed in Research Settings Semaglutide has been explored in laboratory and experimental research settings, and observed responses in some research contexts have included: Nausea Gastrointestinal discomfort Reduced appetite-related observations Vomiting Diarrhea or constipation Bloating or abdominal discomfort Fatigue or lethargy Headaches Injection-site irritation or redness Gastrointestinal & Administration Considerations In some research models, more significant gastrointestinal-related observations have been reported during higher-exposure or administration-escalation protocols
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