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M., Kang, D
In genomic analysis the data come from genome sequencing, but here they come from routine diagnostic, treatment and administrative records of millions of patients
MC1R is a G-protein-coupled receptor (GPCR) that, upon agonist engagement, activates the Gs/adenylate cyclase pathway, increasing intracellular cAMP and activating PKA-linked signalling cascades that upregulate tyrosinase activity and drive eumelanin synthesis the dark, UV-protective form of melanin
Its New York-listed shares gained 2.9% in pre-market trading on Thursday morning, rising above the $100 mark, after publishing its financial results
Am J Resp Cell Mol Biol 29 (6), 771778
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