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The addition of extended-release nicotinic acid to simvastatin prevented the increase in CIMT compared to simvastatin monotherapy
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Designing small molecules able to target multiple receptors might sound difficult, but Septerna says the allosteric binding site it has discovered is even better conserved across all incretin receptors than the site targeted by peptides and other small molecule drugs
The time the test mouse spent interacting with each was recorded for ten minutes, and a sociability index was calculated to quantify its preference for social interaction
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