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222 However, poor solubility and stability restrict its therapeutic application, necessitating the development of nanocarriers or other delivery strategies to improve bioavailability
80 KriegerJPArnoldMPettersenKGLosselPLanghansWLeeSJ
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The American Diabetes Association notes that GH excess (as seen in acromegaly) causes frank diabetes in approximately 20-30% of patients [11], a caution that extends by mechanism to prolonged secretagogue use
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