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Ferritin heavy chain (FTH1) mitigates iron toxicity by sequestering excess free iron

Endogenous Activation of Glucagon-Like Peptide-1 Receptor Contributes to Blood Pressure Control: Role of Proximal Tubule Na(+)/H(+) Exchanger Isoform 3, Renal Angiotensin II, and Insulin Sensitivity

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Designing small molecules able to target multiple receptors might sound difficult, but Septerna says the allosteric binding site it has discovered is even better conserved across all incretin receptors than the site targeted by peptides and other small molecule drugs