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These studies report: Improvement in skin tone and elasticity Mild reduction in melanin index No major adverse effects in studied dosages However, questions remain around: Ideal dosage Duration of therapy Long-term safety Best delivery system Thats why more large-scale, double-blind, placebo-controlled trials are needed to make firm recommendations

Alpha-lipoic acid suppresses osteoclastogenesis despite increasing the receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio in human bone marrow stromal cells