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In endothelial progenitor cells (EPC) derived from human peripheral blood mononuclear cells, high glucose conditions downregulate GLP-1-R and sirtuin 1 ( SIRT1 ) expression, leading to impaired cell functions and increased apoptosis via elevated acetylated p53 levels
& Nahata, M
GLP-1 receptor agonists, including Ozempic, Wegovy, and Zepbound, have gained widespread attention as powerful tools for weight loss and appetite regulation
Avoid self-administration and consult a doctor if pregnant, lactating, or managing chronic conditions
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