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published in Frontiers in Physiology confirmed that BPC-157 dose- and time-dependently increased GHR expression in isolated rat Achilles tendon fibroblasts at both mRNA and protein level, and that GH added to BPC-157-treated fibroblasts produced significant, dose-dependent increases in cell proliferation establishing GHR upregulation as a specific molecular mechanism through which BPC-157 enhances local tissue sensitivity to growth hormone signalling
Physiol Behav (2016) 159:729
: SURMOUNT-5 (NEJM, 2025) : SURPASS-4 (The Lancet, 2021) , SURMOUNT-1 3 (NEJM, 2024) , SURPASS (ADA, 2021) , (Diabetes Care, 2023) GLP-1 30
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