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thiopurine metabolite monitoring required Biologics (TNF- inhibitors): Infliximab (Remicade, J1745), adalimumab (Humira), certolizumab pegol (Cimzia) standard of care for moderate-to-severe CD

Nature Communications (2025) 8

Research in chronic wound modelsincluding diabetic and pressure ulcer experimental systems that had failed standard healing protocolsdemonstrates that TB-500 administration achieves closure rates of 75-85% compared to 35-45% with standard approaches, highlighting potential for addressing impaired healing scenarios

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