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Persistence concerns: Sponsors need early signals when refill activity stops
It allows calories to be absorbed rapidly in the upper intestine before the distal guts braking signals are fully engaged
it is chemically correcting a genetic predisposition toward high-sugar cravings
"From the innovation and effectiveness in capital allocation perspective, most of the capital will not be well spent on the innovation side." Kim drew parallels to what happened with cancer immunotherapy drugs
This matters because lean soft tissue loss comprised 26% to 40% of weight loss in recent trials of GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists
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