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Psychological and environmental factors also play an important role

2022 American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) indications for metabolic and bariatric surgery

Effect of liraglutide on epicardial adipose tissue thickness with echocardiography in patients with obese type 2 diabetes mellitus

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The most frequently reported AEs were gastrointestinal disorders (61% of subjects), which increased in frequency with longer post-dose fasting periods and thus with higher semaglutide exposure