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doi: 10.1038/s41392-020-00349-7

It makes sense to try reducing the dose and monitor weight closely

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These medications also slow gastric emptying, which could potentially affect bowel function, though no direct link to diverticulitis flare-ups has been established

Enzymes like glutathione S-transferases (GSTs), gamma-glutamyl transferases (GTs), uridine diphospho-glucuronosyltransferases (UGTs), thiopurine methyltransferases (TPMTs), and dihydropyrimidine dehydrogenases (DPDs), with elevated levels in cancer cells, show development of MDR to a variety of anti-cancer drugs [55,56,57,58,59,60]