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In patients with T2DM who do not have atherosclerotic cardiovascular disease (ASCVD)/indicators of high-risk, HF, or CKD and who need to minimize hypoglycemia and/or promote weight loss, GLP-1 RAs are generally recommended as a second or third-line option as add-on to metformin therapy
PMID 20021721
PCAC member Elizabeth Rebello, a professor in the Department of Anesthesiology and Perioperative Medicine at the University of Texas MD Anderson Cancer Center, cited the "lack of efficacy data and randomized controlled trials" as her basis for her no vote
This kind of acne usually responds quickly to professional facials
No Observed Effects On: Blood glucose or insulin sensitivity (no diabetogenic effects) IGF-1 levels (remained within normal ranges) Blood pressure or cardiovascular parameters Thyroid function Liver or kidney function markers Important: The absence of growth hormone-related side effects distinguishes AOD-9604 from full-length GH, which can cause fluid retention, joint pain, carpal tunnel syndrome, and insulin resistance
