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Constipation with high-protein intake can occur, especially when protein displaces fiber-rich foods and fluid intake decreases

Be patient with yourself and celebrate progress along the way

Structurally, flavonoids can be classified into several subgroups, including flavonols, flavones, flavanones, isoflavones, and anthocyanins, each with different biological activity profiles (Chen et al., 2023)

Other options include pasireotide (which requires blood glucose monitoring due to hyperglycaemia risk), metyrapone , or ketoconazole (used off-label for Cushing's with liver function monitoring)

Example registry listing (obesity + cardiovascular disease) One publicly listed Phase 3 study is NCT05882045 (TRIUMPH-3) , which evaluates efficacy and safety in participants with obesity and established cardiovascular disease