Its downstream signaling through PI3K/Akt/mTOR and MAPK/ERK makes it relevant to a wide range of research questions in muscle biology, bone physiology, neuroprotection, and metabolic signaling
Additionally, plant-derived antioxidants, such as polyphenols and flavonoids, are increasingly utilized for their antioxidant and anti-inflammatory properties, yet clinical evidence supporting their efficacy remains limited [47, 48]
On an individual level too, the imbalance of supply and demand of these drugs has caused concerns
doi: 10.1007/s10555-025-10257-3 23 ZengYXiangYChenLWenYDengCHuangX
In addition to the regulation of hepatic bile acid synthesis, FGF19 enhances hepatic glycogen synthesis and reduces hepatic glucose output