tirzepatide and kidney issues (Zepbound) showed improved function in obese patients with both chronic kidney disease #heartfailure with preserved ejection fraction, highlighting its potential to address this high-risk patient population. Read more: https Weight Loss Injections for Chronic

The SOUL Trial (Oral Semaglutide): McGuire DK, et al

Whilst a single instance of minor dose reduction is unlikely to significantly impact glycaemic control, consistent under-dosing over multiple injections could potentially reduce the medication's effectiveness

Express Scripts defines medical necessity in its prior authorization criteria (the BMI thresholds, step therapy requirements, and comorbidity documentation described above)

Further, some employers may exclude semaglutide or any weight loss treatments from their formularies, regardless of publicly-available coverage policies

Subcutaneous fat can be pinched and is mostly harmless, while visceral fat acts like a powerful internal engine