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The c-Jun N-terminal kinase (JNK) pathway is activated in human interstitial cystitis (IC) and rat protamine sulfate induced cystitis

The pathogenesis of CVD is heavily influenced by microbial dysbiosis (234)

Many people with LPR do not report classic heartburn but do have throat symptoms that flare after eating or when lying down

The delayed onset reflects bioavailability constraints: oral glutathione is extensively degraded by gamma-glutamyl transpeptidase enzymes in the GI tract, and only chronic dosing saturates these enzymes enough to allow intact tripeptide absorption

This week, two developments pushed peptides closer to the mainstream