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This method was deemed appropriate given the nature of the dataset and the retrospective design of the study
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It randomised 156 participants with early disease to daily subcutaneous lixisenatide or placebo for 12 months, followed by a 2-month washout
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A macule usually does not involve any change in the thickness or texture of the affected skin Melanotic Macules of Oral Mucosa are observed on the lips, in the mouth, on the tongue, etc
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