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These pieces of evidence suggest that after GLP-1 binds to GLP-1R on the surface of islet cells, it is likely to activate the AMPK signaling pathway to act on the nucleus LXR and promote the activation of cell membrane ABCA1, and thus participate in the process of cholesterol efflux from islet cells

Adems de aumentar el riesgo de efectos secundarios, no existe justificacin mdica y puede derivar en el conocido efecto rebote

[] Accordingly, we recommend that future research explore the long-term changes (e.g., 1 year) in the microbiome with the combined treatment