Chronic treatment should be with an oral B12 preparation
Phase 3 trials are underway with potential approval in 2027
Despite increased extramedullary erythropoiesis, reticulocytes failed to mature into red blood cells and accumulated large autophagosomes with engulfed mitochondria [23]
What this means practically: if you're losing weight quickly and your periods are heavier, that's expected physiology, not pathology
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