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doi: 10.14202/vetworld.2023.1541-1545 25 RehmanMSRehmanSUYousafWHassanFUAhmadWLiuQet al

Because SDH is the only enzyme that participates in both the TCA cycle and the ETC, we speculated that the ETC might be compromised in Gclc -deficient FoB, thus explaining the inhibition of SDH and the accumulation of succinate

Mitochondrial ROS, ER stress, and nrf2 crosstalk in the regulation of mitochondrial apoptosis induced by arsenite

Alternatively, when cancer cells use GSH as a cysteine source, they rely less on these pathways (that is, xCT and TXNRD1)