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To identify POMC neurons and GLP-1 receptor-positive neurons, POMC humanized Renilla green fluorescent protein (hrGFP) (The Jackson Laboratory, 006421) and GLP-1 receptor cre::tdTomato (The Jackson Laboratory, 029283) mice were used
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While both medications are effective, several factors explain why tirzepatide often leads to greater or faster weight loss: Dual-hormone activation that enhances appetite and metabolic control Stronger and more consistent hunger suppression Improved insulin sensitivity and energy utilization Reduced likelihood of early weight-loss plateaus Individual differences in hormone response and metabolism These differences dont mean one option is better for everyone
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