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Aplastic Anemia

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CLICK HERE FOR SDS Active Ingredients: Each mL contains: Cyanocobalamin (B12) 1,000 mcg Sodium chloride 0.22% w/v Ammonium sulfate 0.1% w/v Citric acid 0.01% w/v Sodium citrate 0.008% w/v Benzyl alcohol (preservative) 1.0% v/v Indications: For use as an aid in the management of vitamin B12 deficiencies in horses, dogs and cats

Vitamin B12 is crucial for processing nutrients in our cells, especially fats and certain amino acids

Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604