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Mechanism, Uses, and UK Availability Retatrutide is an investigational weight loss injection that works by simultaneously activating three hormone receptors GLP-1, GIP, and glucagon making it the first triple receptor agonist of its kind in clinical development

9 Studies examining body composition changes during GLP-1 therapy have reported a range of results regarding lean mass loss

ura K, Hionaka Y, Sakurai I (1990) Effect of carnitine on size limitation of experimental myocardial infarct - PubMed

The Skin Cancer Foundations statement also notes that additional reports have linked Melanotan II to serious adverse health effects like muscle damage