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Bipolar disorder: A landmark RCT (n=75) found that NAC (1,000 mg twice daily for 24 weeks) produced a significant improvement in depression scores (Montgomery-Asberg Depression Rating Scale) in bipolar disorder as an adjunct to usual treatment (Berk et al., Biol Psychiatry, 2008) [74]
2016;17(11):1561-1567.doi:10.1080/14656566.2016.1204294 10
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Ok, now lets consider a scenario in which you already have a candidate interacting protein, and want to determine which part of it interacts with your protein of interest (Figure 6)
