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Energy in children and adolescents is expended not only on physical activity but also, unlike in adults, on growth and development
Risks include gastrointestinal side effects that may overlap with post-surgical symptoms, increased risk of bile duct stones despite gallbladder absence, and rare but serious complications such as pancreatitis
This latest trial was specifically designed to evaluate the medication in a real-world population: adults with obesity and the painful, debilitating condition of knee osteoarthritis
Novo Nordisk therefore had to create a highly protective approach for the drug, creating a local environment that is less acidic and allows absorption
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