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Laboratory studies monitor how the compound influences enzyme activity, gene expression, and metabolic pathways in tissue-specific experimental models
Hydroxychloroquine (HCQ), which is known for its immunoregulatory, anti-inflammatory, antiproliferative, and anti-photoallergic properties, is commonly used to treat SLE (96, 97)
New blood vessel formation brings oxygen, nutrients, and immune cells to injured tissues
In summary, these studies confirmed that 1907 binds primarily to the helix 23 site on the FAT domain, with weaker binding to the helix 14 site
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