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Compared with the rats treated with APAP alone, rhein treated animals demonstrated significant reduction of the biochemical indicators of liver injury, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea nitrogen (UREA), creatinine (CREA), nitric oxide (NO), and malondialdehyde (MDA)

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Preliminary findings suggest that this peptide-Fc fusion protein enhances NK cell activation and demonstrates ADCC against cancer cells

doi: 10.1073/pnas.2235180100 61 ParkS.YouX.ImlayJ

Most of the available evidence comes from animal and laboratory studies, which suggest the peptide may influence several biological processes involved in healing and recovery