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When clinicians set realistic goals, patients are less likely to feel discouraged if progress slows

22,23 In patients with a normal or low-normal serum vitamin B 12 level, complete blood count results demonstrating macrocytosis, or suspected clinical manifestations, a serum methylmalonic acid level is an appropriate next step 1,2,6,18 and is a more direct measure of vitamin B 12 's physiologic activity

Yerba mate may contribute to a small caloric deficit through increased expenditure, but it cannot replace the sustained appetite reduction and metabolic changes produced by GLP-1 receptor agonism

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GSH and GSSG levels were measured as previously described (21)