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You may begin seeing changes in appetite suppression and possibly energy expenditure within the first few weeks of starting retatrutide, but significant body weight reduction tends to occur over months (24-48 weeks in trials show major changes)
Semaglutide is an injectable glucagon-like peptide-1 (GLP-1) agonist thats administered once a week
What's the process for adjusting medication if side effects are severe
(PubMed) Li S, Chen X, Li Q, et al
doi: 10.3389/fcimb.2021.609722 559 LamminpINiccolaiEAmedeiA
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