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S6H), while cystathionine gamma-lyase (CTH/CSE) was substantially increased at basal level in the ATP6AP1 KO cells, whereas it remained low in WT conditions (Fig

63 Conversely, inhibiting MCTs impedes lactate efflux and diminishes intracellular lactate levels, thereby affecting lactylation levels

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How FOXO4-DRI Works Senescent cells resist natural cell death by trapping the pro-apoptotic protein p53 within the nucleus through interaction with the FOXO4 transcription factor