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If HSPA1 induction is impaired, cells may have a reduced ability to tolerate heat-induced proteotoxic stress, which can contribute to severe damage during spermatogenesis (Williams et al., 2019
Recent studies have demonstrated the immunomodulatory and neuroprotective properties of mTOR inhibitors (Alavi and Fanoudi 2023)
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In some individuals, itching may appear early in the disease, sometimes even before they receive a diagnosis
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