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But in the short run, GI side effects like Nausea, vomiting, and diarrhea can leave you dehydrated, and dehydration can cause a temporary drop in kidney function that shows up as a rising creatinine and a falling eGFR

1, 2, Supplementary Fig

Following this spike, switching rates declined but remained elevated through September 2025 at 1.6% on average before returning to an average baseline level of 0.6% between October 2025 and February 2026

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54 Additionally, miR-7-19488 is significantly upregulated in GDM-derived EVs