Tirzepatide (the active ingredient in Mounjaro and Zepbound) acts on two gut-hormone receptors (GIP and GLP-1) rather than one, and some people are prescribed oral rather than injectable formulations
It is a higher-dose version of Semaglutide, a GLP-1 receptor agonist, also found in other medications like Ozempic
Do not use this drug if you or a family member has had: Medullary Thyroid Carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) FDA Adverse Event Reporting To report side effects, visit www.fda.gov/medwatch or call 1-800-FDA-1088
Vats K, Kruglov O, Mizes A, Samovich SN, Amoscato AA, Tyurin VA et al (2021) Keratinocyte death by ferroptosis initiates skin inflammation after UVB exposure
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