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Cells 8(2):184
Further examination by the same research team compared the actions of GHK-Cu with those of a control compound and vitamin K
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Crystallographic studies have unveiled key PDE1B residues contributing to selectivity and affinity, such as pyrazolo-pyrimidinone, thieno-triazolo-pyrimidinone, and pyrazolo-pyrimidone, which engage the hydrophobic clamp region formed by residues L388, F424, H373, F392, M389, F392, and V417
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