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Here, we suggest that in these disorders, peripheral serotonin levels are low, and elevating them to normal range with L-carnitine is accompanied with reduced fatigue

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Overall, we identified that adjunctive use of bestatin (protease inhibitor), imatinib (tyrosine kinase inhibitor), roflumilast [phosphodiesterase-4 inhibitor (PDE-4)], or palacaparib [Poly(ADP-ribose) polymerase 1, PARP-1 inhibitor] significantly reduced both mortality (compared to the control arm, adjunctive dexamethasone) and neurological deficits (compared to the control arm, TB treatment alone)