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These include the following: IgG4-Related Variant, Juvenile Variant, Fibrous Variant, Hashitoxicosis Variant, and Painless (or silent) Thyroiditis

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It was designed as a stabilized analog of tuftsin (Thr-Lys-Pro-Arg), an endogenous immunomodulatory tetrapeptide derived from the Fc domain of immunoglobulin G

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