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Recycling of BH 4 requires dihydrofolate reductase (DHFR), and if DHFR is inhibited, then BH 4 cooperates with GPX4 to induce ferroptosis [48]

Y., Lee D

Purinergic Signal 12(1):161174 Bosch-Morell F et al (2020) Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration

Keratinocytes make up 95% of the cells in the epidermis and play an integral role in regulating skin irritation

Classical macrophages (M1) are responsible for triggering the inflammatory response via the secretion of pro-inflammatory cytokines and reactive oxygen species (ROS)