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Research studies show that the medication reduces the risk of dementia in patients with type 2 diabetes, prevents neurodegeneration, and improves cognitive functions
In addition, it has been shown that SAG pretreatment significantly prevents CCl4-induced cytotoxicity, is protective in restoring mitochondrial autophagy, and attenuates fibrosis, collagen deposition, hepatocellular damage and organ dysfunction
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Further research is needed to clarify regional differences within the DMH in the expression of GLP-1R and LepR, their upstream and downstream circuits, and how they can contribute to satiation or satiety in different feeding phases
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