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A 2025 preprint showed semaglutide users were about 50% more likely to receive a hair-loss diagnosis than users of Contrave again pointing to an indirect mechanism

Over time, this can reduce overall hydration and make it harder to maintain balance

For people in recovery from eating disorders, these medications could disrupt treatment progress and lead to relapse

Clinical trials show semaglutide users lose approximately 1522% of baseline body weight over 68 weeks, compared to 23% for placebo plus standard diet counseling

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