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[95] In addition to this, mutations in genes related to lysine metabolism have been implicated in several disease states, including pyridoxine-dependent epilepsia (ALDH7A1 gene), -ketoadipic and -aminoadipic aciduria (DHTKD1 gene), and glutaric aciduria type 1 (GCDH gene)
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The dosage of most hypoglycemic medications is gradually increased, if needed, according to a prescribed dosing schedule and therapeutic glycemic targets or until maximal dosage is reached
However, some individuals may experience mild digestive discomfort
doi: 10.1186/s13075-017-1353-6 101 Armas-GonzlezEDomnguez-LuisMJDaz-MartnAArce-FrancoMCastro-HernndezJDanelonGet al
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