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This paradoxical condition fulfils two fundamental tasks: (a) it provides the biosynthesis of FA important for cancer propagation, while ensuring an important source of ATP and Nicotinamide adenine dinucleotide (NADH) by the catabolism of any FA excess

It is commonly upregulated in most cancers, including breast [22], liver [23], prostate [24], pancreatic [25], and lung [26] cancers, and is regulated by oncogenes such as Myc, Kras, and yes-associated protein (YAP)

doi: 10.1016/j.ridd.2023.104439 395 WelinAKSvedinPLapattoRSultanBHagbergHGressensPet al

While Cagrilintide is still undergoing clinical trials, early data is promising