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A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss
Due to its stability, its also widely used in fortified foods
The influence of fasting and energy restricting diets on IGF-1 levels in humans: a systematic review and meta-analysis
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